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What are Amphetamines?



Amphetamine is a psychostimulant, meaning it speeds up the signals traveling between the brain and the body. It enhances concentration, however, if taken in large doses, the effect can be completely different.


Some types of amphetamine is used in medicine to treat conditions such as ADHD and narcolepsy. In the past, amphetamines have also been used to treat Parkinson's disease, but other types of amphetamines, such as speed, are manufactured and distributed illegally. The most potent form of amphetamine is crystal methamphetamine.


How do Amphetamines Look?


Amphetamine can be found in powder, tablet, crystal, and capsule forms.


Amphetamine powder can range in color from white to brown, sometimes gray or even pink. It has a strong smell and a bitter taste.


Illegally manufactured amphetamines may contain various drugs, binding agents, caffeine and sugar. Various new psychoactive substances may also be found in it.


სხვა დასახელებები

Speed, up, uppers, louee, goey, whiz, rack.


Methods of Use


Amphetamines can be used by smoking, snorting, injecting, or orally




Effects


Use of any drug always carries some risk, so it’s important to be careful when taking any type of drug.


The range of effects of amphetamines depends on the following factors:


  • Our height, weight, and health

  • The dose of the received substance

  • Strength and quality of the drug

  • Whether other drugs are taken around the same time

  • Tolerance (how accustomed our body is to receiving amphetamines)

The effects of aphetamine are felt immediately (if smoked or injected) or within about 30 minutes (if snorted or swallowed). At this time you may feel:


Psychological effects

  • Happiness and confidence

  • Increased desire to talk

  • A surge of energy

  • Increased alertness

  • Confusion

  • Paranoia

  • Visual and auditory hallucinations

Physiological effects

  • Dilated pupils

  • Dry mouth

  • Rapid heartbeat and breathing

  • Grinding of teeth

  • Decreased appetite

  • Nausea

  • Sexual arousal


Comedown

During the next 2-4 days after consuming amphetamines, you may experience:

  • Sleep problems and exhaustion

  • Headache

  • Paranoia, hallucinations and confusion

  • Spasms and muscle pain

  • Irritability

  • Rapidly changing mood

  • Anxiety

  • Depression

Using a depressant drug (alcohol, benzodiazepines, cannabis) to cope with these effects can lead to addiction to both types of substances.


Long-term Effects


Long-term use of amphetamines can eventually lead to:


  • Decreased appetite and dangerous weight loss

  • Sleep problems

  • Cavities and tooth loss

  • Frequent illness due to weakened immunity

  • Anxiety and paranoia

  • Depression

  • Increased chance of stroke

  • Liver, kidney and lung problems

  • Financial, professional and social problems.


Mental Health

Studies show that frequent use of amphetamines contributes to the deterioration of mental health.


Long-term use of amphetamine can lead a person to delusional-hallucinatory psychosis (auditory hallucinations and persecutory mania). The cause of such a condition can be chronic insomnia, which disrupts the action of neurotransmitters. Sometimes psychoses are so strong and deep that they can be cured only as a result of long-term psychiatric treatment. Similar long-term treatment may be required for depression caused by amphetamine withdrawal. Such depression is often accompanied by suicidal thoughts, which sometimes turn into suicide attempts.


Psychotic symptoms can sometimes persist for months or even years after a person has given up methamphetamine use. Stress has been found to contribute to spontaneous relapse of methamphetamine psychosis in former methamphetamine users.


Overdose and Risks


Some studies have found a link between amphetamine use and aggressive behavior.


When injecting amphetamines, there is a high risk of tetanus, infection, vein damage, and blood clots. If you share needles with others, you are at high risk of contracting hepatitis B and C and AIDS.


Signs of Amphetamine overdose include:

  • High body temperature and sweating

  • Nausea and vomiting

  • Violent tremors and convulsions

  • Pain in the abdomen, chest and kidney areas

  • Aggressiveness and paranoia

  • Hallucinations

  • Suicidal thoughts

  • Stroke, heart attack and death


Reducing Risks

  • Be sure to test your drug before using it so you know what to be prepared for. You can visit our office or come to our tent at an event to test your drug and find out what you're dealing with;

  • Before consuming the desired dose, it is recommended to take a quarter of the dose and wait for the effects. This way, you will understand how strong that particular batch is;

  • Drink about 500ml (2 medium glasses) of water per hour to avoid dehydration and overheating;

  • If you inject, always use new sterile injection equipment (needle, syringe, filter, etc.). Do not share them even with people you know well. If you both have hepatitis C, sharing is still not recommended - You may be carriers of viruses with different genotypes and become carriers of a new infection by sharing;

  • If you smoke meth, it is necessary to completely vaporize the meth - you should not inhale only the liquid, as this is dangerous for the lungs;


Overdose Management


If you or someone else is experiencing similar symptoms, and you are at an event where a harm reduction organization is present, please seek them out and ask for help. If you don't have a similar organization near you, do the following:


  • In case of high temperature, try to cool the person - apply ice, put them in a cool bath, move them to a cool place;

  • Do not leave the patient alone, call others for help;

  • Have them drink water to prevent dehydration;

  • Take them to a quiet place and reassure them that everything will be fine. Speak calmly, even when they are aggressive;

  • If the person is unconscious - try to bring them to their senses, call them by name, shake them. If you do not get a response, put them in the first aid recovery position and call for emergency medical help


Call emergency medical help immediately if the victim has:


  • Convulsions

  • Severe headache

  • Pain in the chest

  • Shortness of breath

  • Paranoid thoughts and associated aggressive behavior


Mixing Amphetamines with Other Substances


Taking amphetamines with any other type of substance can have unpredictable and dangerous effects on us.


Amphetamines + some depressants: increased risk of arrhythmia and seizures

Amphetamines + alcohol: increased heart rate and elevated blood pressure

Amphetamines + opioids: increased risk of arrhythmia and seizures


Addiction and Tolerance


The excitement and pleasurable euphoria that this substance causes also contribute to the emergence of a psychological dependence on it. The desire to use again is also strengthened by the very unpleasant psychological state that follows the cessation of taking amphetamines. Deteriorated mood and lack of energy encourage us to continue to consume.


Symptoms of physical dependence are slight or fully absent. The only possible symptom of physical dependence is the long-term fatigue and drowsiness that develops after taking amphetamine, which sometimes lasts for several tens of hours.


Withdrawal symptoms usually weaken 1 week after stopping the use, after 1 month they disappear almost completely. At this time you may feel:

  • Increased appetite

  • Confusion and irritability

  • Apathy

  • Muscle pain

  • Tiredness

  • Sleep problems, nightmares

  • Anxiety, depression and paranoia


Sources:

  1. Marshman JA, Brands B, Sproule B, Jacobs MR. Drugs & drug abuse: a reference text. 3rd ed. Marshman JA, Brands B, Sproule B, Jacobs MR, Kevin O'B F, Addiction Research Foundation of Ontario, editors. Toronto: Addiction Research Foundation; 1998.

  2. Darke S, Lappin J, Farrell M. The Clinician's Guide to Illicit Drugs and Health Great Britain: Silverback Publishing; 2019.

  3. Castells X, Blanco-Silvente L, Cunill R. Amphetamines for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev. 2018;8:CD007813-CD.

  4. Ruiz P, Strain EC. Substance Abuse Handbook. Philadelphia: Wolters Kluwer Health; 2014.

  5. Preedy VR. Neuropathology of drug addictions and substance misuse: Volume 2, Stimulants, club and dissociative drugs, hallucinogens, steroids, inhalants, and international aspects. Preedy VR, editor. Amsterdam: Academic Press; 2016.

  6. Campbell A. The Australian illicit drug guide: every person's guide to illicit drugs - their use, effects and history, treatment options and legal penalties. Melbourne: Black Inc; 2001.

  7. Marshman JA, Brands B, Sproule B, Jacobs MR. Drugs & drug abuse : a reference text. 3rd ed. ed. Marshman JA, Brands B, Sproule B, Jacobs MRartrbMRJ, Kevin O'B F, Addiction Research Foundation of O, editors. Toronto: Addiction Research Foundation = Fondation de la recherche sur la toxicomanie; 1998.

  8. Upfal J. Australian drug guide: the plain language guide to drugs and medicines of all kinds. 8th ed. Carlton, Vic, Australia: Black Inc., an imprint of Schwartz Publishing Pty Ltd; 2016.

  9. McKetin R, Leung J, Stockings E, Huo Y, Foulds J, Lappin JM, et al. Mental health outcomes associated with the use of amphetamines: A systematic review and meta-analysis. EClinicalMedicine. 2019;16:81-97.

  10. Colledge S, Larney S, Bruno R, Gibbs D, Degenhardt L, Yuen WS, et al. Profile and correlates of injecting-related injuries and diseases among people who inject drugs in Australia. Drug and alcohol dependence. 2020;216:108267-.

  11. Hahné SJM, White JM, Crowcroft NS, Brett MM, George RC, Beeching NJ, et al. Tetanus in injecting drug users, United Kingdom. Emerg Infect Dis. 2006;12(4):709-10.

  12. Degenhardt L, Charlson F, Stanaway J, Larney S, Alexander LT, Hickman M, et al. Estimating the burden of disease attributable to injecting drug use as a risk factor for HIV, hepatitis C, and hepatitis B: findings from the Global Burden of Disease Study 2013. Lancet Infect Dis. 2016;16(12):1385-98.

  13. World Health Organisation. Lexicon of Alcohol and Drug Terms. World Health Organisation; 1994.

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